Key Lab of Preclinical Study for New Drugs of Gansu Province

By LZU | 01/09/2012 15:25:08 | Views ()

The Key Lab of Preclinical Study for New Drugs of Gansu province, which is under the leadership of Lanzhou University, is one of the first batch province-level key laboratories of Gansu province. The laboratory was prepared to establish in 1999 and authorized by Gansu Province Sci.﹠Tech. Department in 2002. The Scholar of the Cheung Kong, Professor Wang Rui serves as the director and chair professor. Academician Chen Kaixian is the Chairman of Academic Committee. In recent years, great efforts have been made to recruit and foster qualified researchers, and the scientific research team has been optimized continuously. Now, there are 48 scientific researchers in this key lab, among whom 32 researchers have senior title, and 32 researchers have doctoral degree. Notably, the researchers have gotten a lot of honors. There are one Cheung Kong Scholar of the Ministry of Education of China, one winner of the National Outstanding Youth Fund, two Education Programs for New Century Excellent Talents, four Leading Talents of Gansu Province, ten persons of Science and Technology “333” Talent Project and “555” Talent Project of Innovation of Gansu Province, seven Talent Awards for Young Teachers of Gansu Province, three Youth Scientific and Technological Award Winners of Gansu Province, and one winner of the National “May Day” labor medal.

The construction area of this key lab is 13000m2, containing a SPF level animal experiment building. The total value of the instruments and equipment in this lab is over 50 million RMB. During the process of development, four research directions were formed: (1) pharmaceutical chemistry and peptide drugs; (2) the activity screening, pharmacological and toxicological study of new drugs; (3) the study of new drugs and new dosage forms with the combination of traditional Chinese and Western medicine; (4) the study of innovative drugs based on molecular and cellular mechanisms of disease.

According to the above research directions, the corresponding academic teams were established. In addition, an experimental platform consisting six institutions, namely the Institute of Pharmacology, the Drug Design and Synthesis Research Institute, the Institute of Integrated Traditional and Western Medicine, the Institute of Neuroscience, the Molecular and Cellular Pharmacology Research Institute and the Animal Experimental Center, based on which the novel drug research work including the drug design, drug synthesis, pharmacy, pharmacology, pharmacokinetics, the safety evaluation, the molecular mechanisms of the drug action could be conducted.

The researchers of the laboratory undertake a lot of state level, province and ministry level projects, including the Key National S&T Program “Major New Drug Development” of the Ministry of Science and Technology of China, “863 Project”, the National Natural Science Foundation. In addition, numbers of new drug research projects commissioned by enterprises are undertaken by the researchers of the laboratory. Each year, more than 100 SCI research papers are published, over 10 national invention patent items are authorized in average. In the past few years, the laboratory has been awarded by a second class State Natural Science Award and a number of Provincial Natural Science Awards.

Based on the School of Basic Medical Sciences, School of Medicine and School of Life Sciences, doctoral students of four majors, including the Genetics, Integrated Traditional and Western Medicine, Biochemistry and Molecular Biology, Pharmaceutical Chemistry, graduate students of the Genetics, Pathology and Pathophysiology, Integrated Traditional and Western Medicine, Biochemistry and Molecular biology, Pathogenic Biology, Immunology, Pharmacology, Pharmaceutics et al. could be cultivated in this key laboratory. Each year, more than 10 Doctor and 100 master graduate from this lab on average.

According to the principle of “Open, Flow, Associated, Competitive”, the laboratory carries out a wide range of academic exchanges and cooperation in scientific research with the United States, Japan, Hong Kong, Taiwan and many domestic universities, research institutions and enterprises. Now the Key Lab of Preclinical Study for New Drugs of Gansu Province has become an important base for pharmaceutical research in western China.

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