Recently, the research team from the School of Pharmacy, Lanzhou University (LZU) published their latest research findings online titled “Indoloquinoline alkaloid neocryptolepine derivative inhibits Botrytis cinerea by targeting thiamine thiazole synthase” in Science Advances, a sub-journal of the internationally authoritative academic journal Science.
This research not only elucidates the novel antibacterial mechanism of neocryptolepine derivatives but also provides crucial theoretical basis and technical support for the rational design and development of new antibacterial drugs targeting thiamine thiazole synthase.
Paper Link：https://doi.org/10.1126/sciadv.adq5329
